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Discussion Although creatine supplementation has been vastly studied in the last decade, results obtained in these studies show discrepancies in exercise performance improvement in different human cohorts and animal models 2

Moisturizers The American Academy of Dermatology has called the use of unmedicated topical moisturizers an internationally accepted standard adjunctive therapeutic approach to the treatment of psoriasis . In fact, in controlled trials of corticosteroid topical treatments, in which placebo is essentially an unmedicated moisturizer, placebo response rates of up to 47% have been found, suggesting moisturizers alone have a beneficial effect in psoriasis (Menter 2009)

Effective cancer therapies should therefore focus on both restoring wild-type p53 function and targeting the oncogenic signaling pathways activated by mutant p53